Treatment: intrauterine device (IUD)
BioMG follows French guidelines. Adapt it to the guidelines and the tests available where you practise.
Treatment: intrauterine device (IUD)
Laboratory tests
- Chlamydia trachomatis and Neisseria gonorrhoeae NAAT (PCR) on vaginal sample, otherwise on first-catch urine (if STI risk factor or age ≤ 25 years)if neededTo request when the patient has an STI risk factor (partner of less than 3 months, multiple partners in the year, history of STI, unprotected intercourse) or is 25 years or under: the CNGOF does not recommend routine screening before insertion but recommends it in the presence of risk factors [2], and HAS recommends opportunistic Chlamydia screening in sexually active women aged 15 to 25 years, targeted beyond that in case of a risk factor [3]. Depending on practices and exposure, several sites may be sampled (throat, anus, vagina or urine): the NABM provides a code for 2 sites (5302) and one for 3 sites (5303), in place of the single sample (5301) [4].
- Several sites can be sampled depending on practices and exposure (throat, anus, vagina or urine): procedure codes 5302 (2 sites) and 5303 (3 sites).
- Mycoplasma genitalium NAAT (PCR) on vaginal sample (if symptomatic cervicitis before insertion)if neededTo request only if the patient has symptoms of cervicitis before insertion (mucopurulent cervicitis, intermenstrual or post-coital bleeding, dysuria with no other cause): this is the indication retained by the 2021 European guideline [5] and by HAS (2025), which advises against this test in an asymptomatic woman, notably as screening [6]. For the NABM, the combined test with Chlamydia and gonorrhoea (5304) is reserved for acute cervicitis and then replaces the Chlamydia/gonorrhoea PCR alone; the isolated test (5305) is limited to recurrent or persistent cervicitis [4].
- hCGif neededThe Mirena SmPC asks to exclude any possibility of pregnancy, in particular with a pregnancy test [7]; the CNGOF allows insertion at any point in the cycle provided there is certainty that there is no ongoing pregnancy [2].
Do not order
- Glucose, lipid profile, liver enzymes, haemoglobin, thrombophilia screening before a copper or levonorgestrel IUD: class C, do not contribute to safe use [9].
- Testing for Mycoplasma genitalium in an asymptomatic woman, as screening: HAS (2025) does not recommend it outside four indications; the laboratory must not report this result from a multiplex used for screening [4,6].
Sources (16)
- ANSM. DIU - Etat du marché en France en 2021
- Chabbert-Buffet N et al. Contraception : Recommandations pour la Pratique Clinique du CNGOF (texte court). Gynecol Obstet Fertil Senol. 2018 Dec;46(12):760-776
- Haute Autorité de santé. Réévaluation de la stratégie de dépistage des infections à Chlamydia trachomatis. Recommandation en santé publique, synthèse, septembre 2018.
- Assurance maladie. Nomenclature des actes de biologie médicale (NABM), version 105 : actes 5301, 5304 et 5305.
- Jensen JS, Cusini M, Gomberg M, et al. 2021 European guideline on the management of Mycoplasma genitalium infections. J Eur Acad Dermatol Venereol. 2022;36(5):641-650.
- Haute Autorité de santé. Diagnostic biologique des mycoplasmes urogénitaux dans les infections génitales basses. Rapport d'évaluation, actualisation d'avril 2025.
- ANSM, Base de données publique des médicaments. Résumé des caractéristiques du produit MIRENA 52 mg, rubrique 4.4 « Examen médical/consultation ».
- I. Alcaraz, N. Dupin, M. Janier, C. Derancourt, B. Milpied, A. Bertolotti et la Section MST de la SFD. Mycoplasmes génitaux. Février 2016
- Curtis KM, Nguyen AT, Tepper NK, et al. U.S. Selected Practice Recommendations for Contraceptive Use, 2024. MMWR Recomm Rep. 2024;73(3):1-77.
- Bébéar C. Mycoplasma genitalium : quand le rechercher ? Journées SPILF 2019.
- Jensen, J. S., Cusini, M., Gomberg, M., & Moi, H. (2016). 2016 European guideline on Mycoplasma genitalium infections. Journal of the European Academy of Dermatology and Venereology, 30(10), 1650-1656.
- Moore A, Traversy G, Reynolds DL, et al. Recommandation relative au dépistage de la chlamydia et de la gonorrhée en soins primaires chez les personnes non connues comme appartenant à un groupe à risque (Groupe d'étude canadien sur les soins de santé préventifs). CMAJ. 2021;193(16):E573-E584.
- US Preventive Services Task Force. Screening for Chlamydia and Gonorrhea: US Preventive Services Task Force Recommendation Statement. JAMA. 2021;326(10):949-956 (recommandation finale du 14 septembre 2021).
- Faculty of Sexual & Reproductive Healthcare (FSRH). FSRH Clinical Guideline: Intrauterine Contraception. March 2023 (amended January 2025). BMJ Sex Reprod Health. 2023;49(Suppl 1).
- ASHM. Australian STI Management Guidelines for use in primary care : Young people (consulté le 29/10/2026).
- Aaron, K. J., Griner, S., Footman, A., Boutwell, A., & Van Der Pol, B. (2023). Vaginal swab vs urine for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis: A meta-analysis. The Annals of Family Medicine, 21(2), 172-179